The Feasibility Engine for Generics R&D
Stop guessing which routes will work. Start knowing.
When every failed route means lost time, lost yield, and lost opportunity, you can’t afford to gamble. Zymvol’s Feasibility Engine gives generics teams a systematic, data-driven way to predict which enzymatic routes are most likely to succeed—before you ever enter the lab.
De-risk your API pipeline with predictive feasibility assessment
The Problem: Route Development is a Black Box
Process chemistry teams invest months of effort and millions in experiments—only to find out too late that the pathway they chose isn’t viable. Traditional route scouting is trial-and-error, and even AI-only platforms can’t explain why something works (or doesn’t).
The Solution: A Window into Your Pipeline
The Feasibility Engine combines Zymvol’s physics + AI hyperrealistic modeling with a systematic feasibility assessment—so you can instantly see which routes are practical, protectable, and profitable.
No black boxes. No blind bets. Just confident decisions.
How It Works
All the portfolio routes are in-depth evaluated through full-scale molecular analysis to prioritize the top opportunities for an active enzyme to be identified.
Bonus: Biomatched Kits
Each Feasibility Assessment automatically screens the vast public landscape of sequences. Additionally, we also screen your reactions against our partners’ private, commercial-ready enzyme libraries. If a commercial enzyme is a match, we'll identify it for you—creating a fast track from prediction to a lab-validated Proof-of-Concept.
Under the Hood
With our Feasibility Engine, each candidate route is assessed using:
1. Enzyme search technology de-risk
Make sure our technology will deliver an active solution before conducting a full enzyme search campaign.
2. State-of-the-art technology for in depth molecular evaluation
Structure dynamics, explicit solvent, high-accuracy active-site fit and AI-based sequence evaluation guarantees a full in silico characterization.
3. Diverse sequence landscape exploration
Get beyond what's already known to truly novel sequences. This is especially important if IP is key for you!
4. Identification of the most promising opportunities
Invest smartly on the paths with higher confidence to succeed.
More Than an Algorithm: Your Expert Partner
A purely computational score is not enough. The most critical component of the Feasibility Engine is our expert scientific team.
Every assessment is interpreted by a team possessing over 80 years of combined specialized experience and a track record of 180+ peer-reviewed publications. With 12 PhDs from world-renowned institutions, our scientists bridge the gap between theoretical modeling and industrial reality.
Whether it is increasing enzyme conversion by 30-fold or navigating complex IP landscapes to file new patents, our team ensures your data is not just accurate, but actionable. You get the power of our platform, validated by the people who built it.
What you get
The result: a quantitative Feasibility Score (FS) that ranks routes by scientific viability—so you can prioritize with confidence. Our FS score is grounded in our real-world past projects.
80%
Discovery Success rate
90%
Engineering Success rate
Why Generics Companies Choose Zymvol
Reduce risk and cost
Identify dead-ends early and focus only on the most viable routes.
Accelerate timelines
Go from months of wet-lab screening to actionable results in 5 days.
Unlock IP opportunities
Find novel enzymatic routes that improve freedom to operate and create new process patents.
Uphold sustainability standards
Demonstrate PMI and green chemistry improvements to meet ESG goals.
Build internal confidence
Transparent, physics-informed models you can validate and defend in regulatory or IP reviews.
Scale Feasibility with Your Pipeline
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Now, what happens if the Feasibility Assessment says this route is a GO?
The Next Step: From Feasibility to Discovery with BioMatchMaker® (BMM)
The Feasibility Engine (FE) is designed to analyze and prioritize your known pathways. But once you have a viable route, how do you find new, proprietary value and secure a lasting competitive advantage?
That's where the BioMatchMaker® (BMM) comes in.
BMM is our elite discovery engine, engineered to go beyond your current scope. It screens the entire known enzyme landscape—sifting through millions of sequences to find truly novel, high-performing, and often patentable enzymes. This powerful tool takes your FE success to the next level, allowing you to build new assets and secure a powerful competitive advantage.
Results You Can Measure
The Feasibility Engine allows for route selection confidence in days instead of months
Ready to Turn Prediction Into Proof?
De-risk your next API project and prioritize the routes that will deliver measurable yield, cost, and IP advantages.
Schedule Your Feasibility Consultation
Meet with one of our experts and get clarity on your biocatalytic routes today